Beings who possess animal-like powers walk among humans in this alternate universe. These mysterious mutants--the +Anima--are shunned by society... Four outcasts in particular--Cooro, a boy with crow-like powers; Husky, a fish-boy; Senri, a bear +Anima; and a girl named Nana, who wields bat powers--search for others like themselves while trying to gain acceptance in a world cruel to anyone or anything that is different.

 

Cooro
Orphaned as a child, Cooro is the wide-eyed, naive leader of the four. Because of his black wings, many people that see him consider him bad luck or an omen of misfortune.

Husky
Rude, handsome, yet serious (as well as a hater of girls), Husky is the exact opposite of Cooro. Even though his past is shrouded in mystery, deep down he's a good person.

Nana
The last of the four to join the group (as well as the only girl) Nana is a lonely girl with a very sad past. Abused by an alchoholic father, Nana is tormented by the memories of her father's abuse. In fact, it was after she stabbed her father with a pair of scissors and he chased her with a knife that she suddenly changed into a bat +Anima for the first time. But until she fully deals with the past, she finds comfort in being with her new friends.

Senri
The oldest and most mysterious of the group, Senri is a man of few words. He is in constant possession of a mysterious book that he holds very dear, and has an affinity for licking blood and collecting flowers.